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Blood pressure and heart rate should be monitored, particularly in patients with pre-existing cardiovascular conditions, which may be more prevalent in those with longstanding hypothyroidism

N-acetylcysteine (NAC) has antioxidant and anti-inflammatory properties that may help mitigate these effects by reducing oxidative stress and inflammation 39,40,41,42

doi: 10.1038/sj.ijo.0801740

For detailed guidance on temperature excursions, see our article on what happens when tirzepatide gets warm

Semaglutide's number, by contrast, comes from a completed pivotal trial that supported an FDA approval

The truth is the results are not permanent