Clifton GT, Gall V, Peoples GE, Mittendorf EA
LPS recognition by TLR4 is helped by LPS-binding protein (LBP) and CD14, with an indispensable contribution of the MD-2 protein stably associated with the extracellular fragment of the receptor [23]
10.1016/j.molcel.2008.04.009 Mol
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When the hydroxyl group of RNA forms intramolecular hydrogen bonds with phosphate anions, it facilitates the ionization of phosphate groups, thereby enhancing the acidity of RNA