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doi: 10.1210/en.2008-1335 41 BeckIMEVan den BergheWVermeulenLYamamotoKRHaegemanGDe BosscherK

[13] In the setting of acute isoniazid overdose or toxicity, extraordinarily high doses of pyridoxine are used as an antidote: the recommended approach is to administer pyridoxine in a total amount equal to the amount of isoniazid ingested

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It plays a key role in energy production, DNA repair, and cellular function