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This peptide inhibited TGF-1/Smad2/3 and STAT3 pathways, leading to decreased inflammation, tubular atrophy, myofibroblast activation, and fibrotic gene expression (Gwon et al., 2021)

Both preclinical (in vitro and in vivo) and clinical studies were considered for inclusion to provide a broad perspective on the current state of evidence

P v represents the parameters typical value

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For children: The safety and effectiveness of acarbose in people younger than 18 years havent been proved