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However, chronic high-dose use beyond 12 months without periodic reassessment can mask underlying deficiencies or metabolic dysfunction if you require continuous lipotropic support to maintain normal fat metabolism, the underlying cause (hypothyroidism, insulin resistance, genetic methylation impairment) should be investigated

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3 A wider group of doctors, including general practitioners (GPs), will start to prescribe the new AOMs for their patients over the next few years in the UK