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CJC-1295 (no DAC) binds GHRH receptors on pituitary somatotrophs, initiating GH secretion through the cAMP/PKA signaling cascade 2

Dehydration and Volume Depletion : The gastrointestinal side effects of semaglutideparticularly nausea, vomiting, and diarrheacan lead to dehydration and intravascular volume depletion

Metoclopramide, an FDA-approved prokinetic for gastroparesis, carries a boxed warning for tardive dyskinesia and should generally be limited to 12 weeks or less of therapy

Data availability The datasets are available from the corresponding authors upon reasonable request

Microglia, the resident immune cells in the CNS, function as brain macrophages and are essential in modulating neuroinflammation when activated under inflammatory conditions [100, 101]

So, okay, fingers crossed