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Additionally, several novel GLP-1 RAs, including efpeglenatide, ecnoglutide, and orforglipron, are under development and have entered preclinical and clinical trials

Long-term monitoring should include: Assessment of thyroid nodules Evaluation of calcitonin levels when indicated Routine clinical surveillance 12.2 Monitoring for Signs of Pancreatitis Acute pancreatitis is a rare yet serious adverse event

6 Davies M et al

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