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Multifunctional nanoplatforms can promote polarization of tumor-associated macrophages toward the M1 phenotype, activate dendritic cell maturation, enhance cytotoxic T lymphocyte infiltration, and suppress proliferation of immunosuppressive cell populations (regulatory T cells, myeloid suppressor cells, etc.), thereby reversing immune suppression

The injection can consist of material in liquid or foam form

To further enhance the BBB properties of the models, the medium was supplemented with cARLA (250 M 8-(4-chlorophenylthio)adenosine 3,5-cyclic monophosphate sodium salt, 17.5 M Ro-20-1724, 3 mM LiCl, 3 M A83-01

Batch-specific Certificate of Analysis available on request

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