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Its efficacy is well-documented in the scientific literature

Platinum-based chemotherapy is highly effective for treating the disease and is typically administered before RPLND [276]

Endocr Metab Immune Disord Drug Targets

As a permanently charged quaternary cation the compound is water-soluble and requires no organic cosolvent for aqueous work, though DMSO stock solutions are common in cell-based screening

Conclusion Whilst severe B12 deficiency has a clear clinical picture with characteristic haematological and/or neurological features, establishing mild or borderline deficiency can be problematic as serum levels are maintained at the expense of tissue concentrations, and therefore serum levels of B12 may be in the low normal or borderline range despite a deficiency

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