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Strategies that deplete GSH, such as using inhibitors like BSO which is inhibitor of -glutamylcysteine synthetase (-GCS) , the rate-limiting enzyme in glutathione (GSH) synthesis or by combining prodrug activation with GSH depletion in nanosystems, have shown promise in overcoming MDR and improving chemotherapy effectiveness [72]
Aim for consistent intake throughout the day
How should I reconstitute and store GHK-Cu
For a broader overview of the vitamin C side of the equation, see What is the Best Vitamin C Pill to Take for Your Health?.
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