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Natural GLP-1 lasts only a minute or two before an enzyme inactivates it, so most of its signal stays near the gut

Antimicrob Agents Chemother

PMID 42065516

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Regul Pept 181:5066 Bdis B, Kardi O, Nmeth P, Dohoczky C, Kolega M, Mzsik G (1997) Evidence for direct cellular protective effect of PL-10 substances (synthesized parts of body protection compound, BPC) and their specificity to gastric mucosal cells