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PCOS and Semaglutide Women with polycystic ovary syndrome (PCOS) often experience improved menstrual regularity on semaglutide, contrasting with typical users who may develop irregularities

Fatigue during initial treatment or rapid weight loss could also temporarily affect libido, though these are not direct hormonal effects of the medication

Gonalves-Dias et al., 2023

Cortisol is a stress hormone that, when chronically elevated, promotes fat storage (particularly visceral fat), breaks down muscle tissue, impairs sleep, and suppresses immune function

The regulatory landscape for peptide therapy continues to evolve, and patients should discuss current availability with their prescribing clinician

Of note, other antihyperglycemic agents used in the management of T2D have been investigated in management of asthma