Other GLP-1 agonists like semaglutide (known by its brand names Ozempic and Wegovy) only target the GLP-1 receptor
[1] Weight loss outcomes with semaglutide based on diabetes severity using the individualized metabolic surgery score, Ghusn, Wissam et al., eClinicalMedicine, Volume 72, 102625 [2] [3] Weight loss outcomes with semaglutide based on diabetes severity using the individualized metabolic surgery score, Ghusn, Wissam et al., eClinicalMedicine, Volume 72, 102625 [4] EP 2866825 [5] T 1701/22 Other News
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It has not been tested for safety, quality, or effectiveness so we dont know how serious any possible side effects could be
Clinical trial participants reported the most discomfort when they first started taking tirzepatide, or when they increased their dose