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One prevailing theory is that tirzepatide is an imbalanced and biased GLP-1 RA with very low efficacy for recruitment of -arrestin, whilst is acting as an unbiased GIP agonist with full efficacy for -arrestin recruitment [51, 52]
Sources: Aronne et al., 2024
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For example, semaglutide is composed of 31 amino acids (Figure 1), and tirzepatide is even larger with 39 amino acid residues
Freezer storage: Unreconstituted ipamorelin can be frozen at -4 degrees Fahrenheit (-20 degrees Celsius) for long-term storage
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