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While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control

and is useful in some cases of allergies by virtue of its ability to reduce histamine release

This mechanism has been linked with reduced fat cell size , increased insulin sensitivity , and improved overall metabolic efficiency

(Springer, Dordrecht, The Netherlands), 209229

Recently, it even managed to inhibit tumor growth and malignant cancer cells in mice

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