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The SURMOUNT clinical trial program, which included over 5,000 participants treated with Zepbound for up to 72 weeks, did not identify any confirmed cases of MTC

As impressive as these treatments have been, research has raised questions over what else they might be doing to the body including increasing the risk of bone and joint conditions, and sudden sight loss

Adverse psychiatric effects associated with GLP-1 RAs, including depression, anxiety, and suicidal ideation, are noted in pharmacovigilance analyses, with variations among different GLP-1 RAs

In Phase 3 trials, constipation affected up to 26.1% of people taking retatrutide, compared with 10.9% on placebo

Structure-function relationship and physiological role of apelin and its G protein coupled receptor

GIP and GLP-1 are hormones that are naturally produced in the gut and play important roles in the regulation of glucose metabolism and satiety