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suppression of TNF--induced inflammatory cytokine secretion

43,45,48,49,51,53,54,61 iNOS (inducible nitric oxide synthase), a marker of the proinflammatory M1 phenotype, was suppressed by GLP-1/GIP 44 and exenatide, 54 and Iba-1 (ionized calcium binding adaptor molecule 1) was attenuated by exenatide 43,45,49 and semaglutide