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Dysbiosis, or an imbalance in gut microbiota, is associated with metabolic diseases, especially T2DM, and can cause changes in the signaling pathways of intestinal hormone secretion, leading to various health problems [156]

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A doctor or nurse practitioner should be able to provide a solid medical reason for a monthly visit, for example, a situation that requires close monitoring, such as prescribing a weight loss medication for someone with insulin dependent diabetes

People with medical conditions, a history of disordered eating, diabetes medications, pregnancy, kidney disease, or complex health histories need medical oversight

This weekly schedule is consistent with other long-acting incretin-based therapies and is designed to maintain stable drug levels throughout the week

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