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A Wide Range of Individual Outcomes Average figures can obscure a great deal

If semaglutide does indeed have long-lasting effects on brain chemistry, this could influence its use in treating not only obesity and diabetes but also conditions like depression or addiction, where dopamine plays a central role

Code availability The source code used to analyze the bulk RNA-seq data is available at Change history 30 October 2025 The original online version of this article was revised: In the originally published version of this article, Figure 4 contained an error in the RNA-seq analysis

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Trends Immunol 2018;39:489502