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This biosensor was targeted to specific subcellular regions, including the nucleoli, stress granules, p-bodies, nuclear paraspeckles and Cajal bodies, along with their respective surrounding environments, i.e., the cytosol and nucleoplasm

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Additionally, ADP-ribosylation factor 6 (ARF6), a downstream effector of the KRAS/ERK signaling pathway, promotes the proliferation of PDAC cells

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Keating MJ, O'Brien S, Albitar M, Lerner S, Plunkett W, Giles F, Andreeff M , Cortes J, Faderl S, Thomas D, Koller C, Wierda W, Detry MA, Lynn A, Kantarjian H