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Unfortunately, GLP-1 is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4), which limits the therapeutic efficacy of native GLP-1 (Deacon et al., GLP-1R agonists The GLP-1R agonists mediate their action by acting directly on the GLP-1R

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While no medical treatment is completely without risk, receiving care within a clinical environment provides safeguards that simply arent available when individuals attempt to self-manage peptide therapy