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Mechanisms that induce resistance to glutamine-targeting therapies Although targeting glutamine metabolism is a promising therapeutic approach, few drugs have been developed

Ionescu, M., & Frohman, L

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NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model

Furthermore, lesions of the rodent Edinger-Westphal nucleus greatly attenuate ethanol preference 24,25

While IGF- 1s direct anabolic effects on muscle have been well established, our results highlight its underappreciated role in maintaining microvascular integrity and regulating muscle perfusion