The sooner treatment begins, the better the outcome
Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease
Additional benefits include metabolic enhancement without growth hormone side effects, no impact on blood glucose or insulin sensitivity, potential increases in energy expenditure through thermogenic mechanisms, and compatibility with athletic training and performance goals
NNMT is an enzyme that works in your cells to manage energy and metabolism
Association of vitamin B12, folate, and sulfur amino acids with brain magnetic resonance imaging measures in older adults: a longitudinal population-based study
Their body mass index was higher as well