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Hunger hormones (ghrelin) increase, satiety hormones decrease, metabolic rate drops, and your brain becomes more responsive to food cues

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Data obtained by the AVANT trial of adjuvant bevacizumab in colorectal cancer shows evidence of higher incidence of relapses and deaths in bevacizumab treated patients due to disease progression suggesting an increased tumor aggressiveness after anti-angiogenic therapy [288]

Patients taking anticoagulants or antiplatelet medications should not discontinue these drugs without explicit guidance from their prescribing physician, as the cardiovascular benefits typically outweigh the inconvenience of increased bruising