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They warn that the lack of rigorous clinical trials and standardized protocols raise serious safety concerns, including the risk of hepatotoxicity (liver damage caused by chemicals) and allergic reactions like anaphylaxis

Rossi, R., Giustarini, D., Milzani, A

Isolated GH axis intervention without attention to these interacting systems may produce suboptimal outcomes

It is used in extended observational studies in laboratory environments

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