Table 7 also lists the extra loss of essential minerals, in terms of the fraction of the Recommended Daily Allowance (RDA) lost each day, based on two reasonable assumptions: 1) averaging the loss between the 1 st and 9 th dose, and 2) assuming a daily urinary excretion of 500 mcg of creatinine, which is typical of a 60-pound child
In many cases, the overall effect on the medication's therapeutic action is not significant, but the efficacy of some drugs (see below) may be altered
These differences reflect normal biological variability rather than a failure of the medication
The bodys digestive system is incredibly efficient at its job, but it cannot tell the difference between an efficacious, protein-based medicine and a piece of food
Injecting contaminated medication could potentially lead to local infections at the injection site or other health complications
The dissolution time can vary depending on individual factors, but generally, the troche should dissolve slowly over a period of 15-30 minutes