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In type 2 diabetes-related cervical cancer tissues, a high-glucose microenvironment induces the upregulation of PSMA2, phosphorylated IB, and phosphorylated P65 expression, thereby promoting tumor progression, while Ex-4 can effectively inhibit this pathological process [120]

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Interestingly, in addition to the potential cognitive benefits and protective effects against Alzheimer's disease (45) (46) (47) (48) (49), methylene blue appears to have more general neuroprotective memory-enhancing properties and is being studied as a therapeutic agent for improving brain function after concussion and traumatic brain injury (50) (51) (52) (53)

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The pain is not indicative of structural damage