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Hokari, F

Immunomodulation with obesity and ferroptosis With the continuous in-depth study of obesity, the importance of AT immune cells as a key hub for regulating the AT environment has become recognized

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Previous studies indicated that lysosomal iron is released and translocated into the mitochondria contributing to MPT in APAP-induced injury ( 2+ uniporter MCFU plays a key role in APAP-induced oxidative stress, mitochondrial dysfunction, and hepatocellular death ( 2+ from lysosomes followed by uptake into mitochondria via MCFU is a key mechanism in APAP-mediated hepatotoxicity

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E.WangS.NakshatriP.et al (2009)