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PDRN works at a cellular level, unlike traditional hydrating serums that work on the surface

(2019) 132:jcs222570

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Therefore, overuse and rapid depletion of glutathione results in a deficiency of methylcobalamin and a number of neuropathological disease states related to a downstream neurotransmitter imbalance (James et al., 2004

Geelen JM, Monnens LA, Levtchenko EN (2002) Follow-up and treatment of adults with cystinosis in the Netherlands