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Cynthia Maxwell MD, MBA, FRCSC, DABOM (Obesity Medicine), is the Medical Content Director of First Exposure, the Vice President, Medical Affairs & System Transformation and Lead Medical Executive at Womens College Hospital and Professor, Faculty of Medicine, Department of Obstetrics and Gynaecology and Division of Maternal Fetal Medicine at the University of Toronto

At the start, when the dose was low, the effects were slow, Steward said, and for the first few months she tracked her calories and macros

34,35 Subsequently, GLP-1 undergoes enzymatic degradation facilitated by dipeptidyl peptidase IV (DPP-4), leading to the loss of its biological efficacy

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This idea was further supported when similar phenotypes were observed across ferroptosis-sensitive and ferroptosis-resistant cancer cell lines (Extended Data Fig