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In DKD, upregulation of local angiotensin II in the renal tubule, activation of vascular endothelial growth factor (VEGF), and reduction of nitric oxide (NO) (60) can lead to constriction of both the afferent and efferent arterioles, as well as the interlobular arteries, compromising blood flow regulation

J Acad Nutr Diet.2014 Oct;114(10):1594-600 8

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Delaying your period with hormonal birth control pills or norethisterone does not reduce your fertility once you stop taking them

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