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Plates were imaged on a CellInsight CX5 HCS platform (Thermo), and counts of nuclei were used as the readout
[3] The scientists note that results together suggest that myostatin suppresses both basal and IGF-1-stimulated proliferation of both WAT and BAT preadipocytes, actions that are again similar to those in muscle satellite cells. Receptor Grade IGF-1 LR3, due to its speculated stability, may potentially counteract Myostatin by activating MyoD, a muscle protein normally triggered through prolonged physical strain
Brown E, Heerspink HJL, Cuthbertson DJ, Wilding JPH
Best for : Patients seeking regenerative support, improved firmness, and overall skin quality improvement with a generally well-tolerated ingredient
This research post is the original announcement