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The FDA maintains a drug shortage database based on several key criteria: When manufacturers report anticipated disruptions or discontinuances in drug production When the FDA becomes aware of significant supply issues through market surveillance When healthcare providers or patients report consistent difficulty obtaining medications When a drug's demand significantly exceeds available supply On October 30, 2024, Novo Nordisk confirmed that all doses of Wegovy and Ozempic are now listed as available in the U.S., although the company cautioned people may still experience variability in filling their prescriptions
While this effect can aid in managing diabetes and promoting weight loss, it can also result in adverse complications in some patients
North America leads the first commercial wave, while parts of Europe and East Asia are likely to shape the next phase of premiumization and format design
Holmes et al, 1998