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TP73 expression rises by 938%, USP29 (which stabilizes the critical p53 tumor suppressor) jumps 1,056%, and BRCA1 and PTEN both see significant upregulation
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Although prior reviews have established the fundamental involvement of ferroptosis in PD, our work extends the existing literature through several distinct contributions ( -syn aggregation and ferroptosis, elaborating not only on how -syn disrupts iron homeostasis and drives lipid peroxidation, but also how iron and its associated oxidative metabolites directly stabilize -syn oligomers and accelerate fibrillation
Nat Neurosci (2014) 17:17207
Reconstitute lyophilized powder with sterile water or appropriate solvent under sterile conditions
Lyophilized proteins or larger peptides might need buffers to maintain structure, while small peptides often dissolve readily in water
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