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Stefan Macher: declares no conflict of interest relevant to this study
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The study design itself reflected the confidence Lilly had in retatrutide's potential
Discussion This is the case of a 44 year old man with extreme, refractory obesity who successfully underwent a 21 day water fast in combination with GLP-1 treatment prior to bariatric surgery
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further notes that NICE CKS guidance states that treatment of B12 deficiency in people with neurologic involvement should include injections on alternate days until there is no further improvement
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