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Exposure to outdoor elements, primarily ultraviolet (UV) irradiation and oxidative stress is the main cause for photoaging

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Hassan et al., The micronutrient Mg 2+ also has been proposed as a treatment for NIHL, not only for its function as a potential cochlear vasodilator but for other pharmacological properties, which include modulation of NMDA glutamate receptors and the regulation of calcium influx into hair cells, preventing or reducing apoptosis (Cevette et al., 2006