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[7] [8] Within cells, it localizes to the cytoplasm and mitochondria

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Although the above discussed studies suggested a considerable association between the selenium-induced GPx level and the radiation resistance of cultured cells and murine models, it can be argued that the direct cause and effect relationship between GPx activity/expression and radiation toxicity was lacking in these studies

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Prevention of glutathione depletion-induced apoptosis in cultured human RPE cells by flupirtine