Multiple doses are common at the start of treatment, with monthly maintenance injections afterward
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This is most relevant when vitamin B12 deficiency is being corrected and broader B-vitamin support is clinically appropriate, where symptoms include a combination of fatigue, neurological features, and stress, or where rapid repletion and functional support are desired
Am J Med 1989;88:141-4 Grindulis KA, Calverley M, Cox C
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