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This may relate to the fact that patients with the obesity phenotype of HFpEF are, on average, a decade younger than those with HFpEF without obesity

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Activation of these receptors has been shown to modulate the production of pro-inflammatory cytokines and promote anti-inflammatory pathways

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Further Reading For wider scientific background on peptide and incretin research, researchers can review public information from PubMed and ClinicalTrials.gov