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According to this hypothesis, 5OP would signal through pH modulation to activate PhoPQ, upregulating the mgtCBR operon, which would then regulate c-di-GMP, cellulose and cellular aggregation
May;4(2):288-314
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This makes the topic a great choice, as it combines what patients are curious about with practical clinical advice
Symptoms can be intermittent, lasting days, a few weeks or months, though generally they can last years
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