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Subsequent rises in IGF-1 concentrations were noted, persisting for one to two weeks, with prolonged activity observed in repeated exposures

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In contrast, the powerful beta cell action of exendin-phe1 provides a potential means to avoid tolerability issues associated with high doses of other agents, and might therefore be a novel therapeutic option for T2D

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Petersen N, Frimurer TM, Terndrup Pedersen M, Egerod KL, Wewer Albrechtsen NJ, Holst JJ, et al