Ansley DM, Wang B
For topical cosmetic use on intact skin , the answer from the available evidence is that systemic copper absorption is minimal
Apply to clean, dry skin once weekly
In a broad sense B12 refers to a group of cobalt-containing vitamer compounds known as cobalamins: these include cyanocobalamin (an artifact formed as a result of the use of cyanide in the purification procedures), hydroxocobalamin (another medicinal form), and finally, the two naturally occurring cofactor forms of B12: 5'-deoxyadenosylcobalamin (adenosylcobalaminAdoB12), the cofactor of Methylmalonyl Coenzyme A mutase (MUT), and methylcobalamin (MeB12), the cofactor of 5'-methyltetrahydrofolate-homocysteine methyltransferase (MTR)
Journal of Agricultural and Food Chemistry, 63 (14), 3752-3756
Stage-Specific changes in the water, Na+, Cl- and K+ contents of organelles during apoptosis, demonstrated by a targeted cryo correlative analytical approach