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Microsomal prostaglandin E 2 synthase-1 (MPGES-1), a member of the MAPEG family, is implicated in the biosynthesis of prostaglandin E 2 a metabolite of arachidonic acidinvolved in several biological functions

Myth: You don't need glutathione because your body makes it

This loop shifts the GSH thiol group away from Cys A allowing the thiol groups of GSH and Cys A to coordinate a labile FeS cluster in a cluster-bridged dimeric holoprotein

"Toxicity by NSAIDs

As soon as the catalytic mechanism of GPx was discovered, the design and development of synthetic compounds mimicking GPx-like activity became an active research area [71,72,73]