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It has been used in medicine for over 100 years in anesthesia, gastroenterology, pathology, histology and pain medicine

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For many states, DSHP and DSIP were a key part of their broader strategies to address healthcare provider shortages, strengthen care delivery systems, and support vulnerable populations through upstream public health and health-related services interventions

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B12 is water-soluble, with excess typically excreted in urine, and anxiety is not listed as a recognised adverse effect in MHRA product information