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Exceptions were observed when Liraglutide at 10 nM enhanced the proliferation of hMSC pretreated with LPS to mimic an inflammatory setting [4], and in experiments performed by Wang et al., where Liraglutide at 10 nM showed no effect on the proliferation of human bone marrow-derived stem cells (hBMSC) [21]

This risk is heightened by genetic variants such as the OATP1B1 R57Q polymorphism, which impairs drug transport and can lead to systemic toxicity (62, 63)

Clinical data show reductions in liver fat and improvements in metabolic markers