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This makes it a subject of significant interest in wound healing and chronic inflammation research

M.ZhaoY.GinghinaC.et al

[6] Davies, M., et al

Make sure you maintain a regular injection schedule for consistent results

The "gradual decline" group (approximately 40-50% of users) represents modal experience where benefits slowly regress toward pre-treatment baseline over 4-8 months, typically affecting users who completed shorter treatment courses (2-4 months), used lower concentrations or inconsistent application, possessed moderate to severe baseline skin damage requiring ongoing support, maintained adequate but not optimal complementary skincare, experienced significant lifestyle stressors affecting skin health including poor sleep or high stress, and faced genetic or age-related collagen production limitations

Some practitioners prefer this approach for more severe injuries or when seeking maximum healing support