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5 For example, recent preclinical and clinical observations highlight the role of gut-derived peptides such as GIP, GLP-2, and to a lesser extent, GLP-1 in the maintenance of overall skeletal health ( Figure 2 ), 6,7,8 opening new avenues for the understanding and potential treatment of bone disorders
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These findings suggest that such probiotics may promote NLRP3 activation through integrated signaling pathways involving cross-talk between TLRs and NOD receptors (266)
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