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(ClinicalTrialsgov, U.S
Thats why weve put together a helpful guide on whats known about the potential benefits, the best way and time of day to take it, what to watch out for, and who should avoid it altogether
Overall, results from the cardiovascular outcomes trials (CVOTs) completed for all marketed GLP-1 RAs in type 2 diabetes support a benefit in HF specifically in addition to the approved use in broad CVD risk reduction in people with type 2 diabetes ( The biology and pharmacology of GLP-1 GLP-1 is a major peptide hormone of the incretin system
Beyond glycemic control and weight reduction, GLP-1RAs confer cardiovascular, renal, and metabolic benefits, positioning them among the most promising therapeutic options, particularly in obese patients with diabetes (111)
This frequency may seem excessive, but the first three months represent the highest-risk period
It works on both GLP-1 and an extra hormone called GIP (glucose-dependent insulinotropic polypeptide)
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