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Many compounding pharmacies require prescriber attestation regarding patient suitability, and some may decline to fill prescriptions for patients with advanced liver disease due to liability concerns
Mandal et al., 2022
Neuroscience, 460 , 161166
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The honest research caveat is that "theoretically additive" is not "experimentally additive" and a researcher who needs to claim synergy must run the combination versus the components in their own model
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