Diarrhea specifically affected 9% to 20% of participants across dose groups in Phase 2
Xie, Y., Bowe, B
Contact your GP or prescribing clinician if you notice: Mood changes that feel disproportionate or unusual for you Irritability or emotional instability affecting relationships or work Anxiety that develops or worsens after starting treatment Sleep disturbances, particularly insomnia or excessive sleeping Symptoms of hypoglycaemia if you have diabetes (confusion, tremor, sweating, rapid heartbeat) Your healthcare provider can assess whether symptoms relate to the medication, underlying mental health conditions, or other factors
Making simple swaps like choosing whole grain bread instead of white bread, adding beans to salads, or starting the day with a fiber-rich breakfast bowl can help reach the recommended daily fiber intake of 25-30 grams
doi:10.1016/j.amjmed.2009.03.015 Kooy A et al (2009): Long-term effects of metformin on metabolism and microvascular and macrovascular disease in patients with type 2 diabetes mellitus
Although it is not yet clear whether micronutrient supplementation has beneficial effects on various cognitive domains, it is well established that micronutrient deficiencies, especially B vitamin deficiencies, have adverse effects on cognition